Josh Riback (PI)

"I am a biophysicist interested in understanding the principles governing the formation of both large complexes (e.g. RNA-protein complexes) and biological condensates through application and advances in the tools of polymer physics and physical chemistry."

Starting August 2021, Josh will join the Department of Molecular and Cellular Biology as an Assistant Professor and CPRIT Scholar at Baylor College of Medicine. Previously Josh was a postdoctoral scholar with Clifford Brangwynne at Princeton University where he elucidated principles of polymer biophysics that both govern the assembly of large macromolecular nucleic acid protein complexes within biological condensates and the interplay between their assembly and condensate formation in living cells. Prior to this work, he obtained a PhD in the Biophysical Sciences at the University of Chicago, co-mentored by Drs. Tobin Sosnick and D. Allan Drummond, studying intrinsically disordered regions/proteins connecting their extent of collapse (or lack thereof) to biochemical and cellular phenomena including phase separation, protein (mis-)folding/aggregation, and cellular fitness. During his undergraduate studies, he majored in Biophysics at Johns Hopkins University (2013) and worked in Dr. Bertrand Garcia-Moreno’s lab studying the thermodynamics of buried ionizable groups within proteins. Outside of the lab, he enjoys spending time with his wife, two children, and two cats.